Thermo Fisher Scientific PAK5 Polyclonal Antibody
PAK5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며 인간, 마우스, 랫트 반응성. 액상 형태, 1 mg/mL 농도, -20°C 보관. 세포골격 및 신호전달 연구용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PAK5 (Accession Q9P286), corresponding to amino acid residues L576–I626 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818614 |
Product Specific Information
Antibody detects endogenous levels of total PAK5.
Target Information
PAK7 (KIAA1264) is implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling.
This kinase contains a CDC42/Rac1 interactive binding motif and binds CDC42 in the presence of GTP.
It is predominantly expressed in the brain and promotes neurite outgrowth, suggesting a role in neurite development.
PAK7 associates with microtubule networks and induces microtubule stabilization.
Its subcellular localization is tightly regulated during cell cycle progression.
Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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