Thermo Fisher Scientific PDE4B/PDE4C/PDE4D Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human PDE4B(Accession Q07343), corresponding to amino acid residues G36-A86. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE4B/PDE4C/PDE4D,uniProtId:Q07343-1,ncbiNodeId:9606,antigenRange:36-86,antigenLength:736,antigenImageFileName:PA5-99682_PDE4BPDE4CPDE4D_Q07343-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99682_PDE4BPDE4CPDE4D_Q07343-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:PDE4B/PDE4C/PDE4D,uniProtId:Q08493-1,ncbiNodeId:9606,antigenRange:1,antigenLength:712,antigenImageFileName:PA5-99682_PDE4BPDE4CPDE4D_Q08493-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99682_PDE4BPDE4CPDE4D_Q08493-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:PDE4B/PDE4C/PDE4D,uniProtId:Q08499-1,ncbiNodeId:9606,antigenRange:1,antigenLength:809,antigenImageFileName:PA5-99682_PDE4BPDE4CPDE4D_Q08499-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99682_PDE4BPDE4CPDE4D_Q08499-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818615

Product Specific Information

Antibody detects endogenous levels of total PDE4B/C/D.

Target Information

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.