
Thermo Fisher Scientific PDE4B/PDE4C/PDE4D Polyclonal Antibody
Thermo Fisher Scientific의 PDE4B/PDE4C/PDE4D 폴리클로날 항체는 인간 및 마우스 시료에 반응하며, WB, IHC, ICC/IF에 사용 가능합니다. Affinity chromatography로 정제된 고순도 항체로, PBS/glycerol 버퍼에 보존되어 안정적입니다. 연구용으로만 사용됩니다.
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- PA599682
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PDE4B (Accession Q07343), corresponding to amino acid residues G36–A86 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818615 |
Product Specific Information
Antibody detects endogenous levels of total PDE4B/C/D.
Target Information
This gene belongs to the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates cellular concentrations of cyclic nucleotides and plays a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and promoter usage result in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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