Thermo Fisher Scientific VAV1 Polyclonal Antibody
Human VAV1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, 보존제가 없는 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminus of Human VAV1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788357 |
Product Specific Information
- Preservative-free formulation.
- Sodium azide (final concentration 0.05%–0.1%) addition recommended to prevent contamination.
- Specificity: Human VAV1.
Target Information
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play roles in normal-tension glaucoma and adult-onset primary open-angle glaucoma. It interacts with adenovirus E3-14.7K protein and may utilize TNF-alpha or Fas-ligand pathways to mediate apoptosis, inflammation, or vasoconstriction. Optineurin may also function in cellular morphogenesis, membrane trafficking, vesicle trafficking, and transcription activation through interactions with RAB8, huntingtin, and transcription factor IIIA. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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