Thermo Fisher Scientific DCP1A Polyclonal Antibody
Thermo Fisher Scientific의 DCP1A Polyclonal Antibody는 Western blot 및 ELISA에 적합한 토끼 유래 다클론 항체입니다. Human, Mouse, Rat에 반응하며, 세포질 및 핵 내 P-body에서 DCP1A 단백질 검출에 사용됩니다. 고순도 Affinity 정제 및 안정한 PBS/glycerol buffer로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 303–582 of human DCP1A (NP_060873.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.23 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914665 |
Product Specific Information
- Positive test controls: HepG2, Jurkat, Mouse brain, Rat brain
- Subcellular localization: Cytoplasm, Nucleus, P-body
Immunogen sequence:
NEKHAPTYTI PLSPVLSPTL PAEAPTAQVP PSLPRNSTMM QAVKTTPRQR SPLLNQPVPE LSHASLIANQ SPFRAPLNVT NTAGTSLPSV DLLQKLRLTP QHDQIQTQPL GKGAMVASFS PAAGQLATPE SFIEPPSKTA AARVAASASL SNMVLAPLQS MQQNQDPEVF VQPKVLSSAI PVAGAPLVTA TTTAVSSVLL APSVFQQTVT RSSDLERKAS SPSPLTIGTP ESQRKPSIIL SKSQLQDTLI HLIKNDSSFL STLHEVYLQV LTKNKDNHNL
Target Information
Signal transduction of TGF-beta superfamily members is regulated by Smad proteins. Smads influence gene transcription by relaying signals from the cell membrane to the nucleus. Smad4 plays an essential role in TGF-beta-induced transcriptional activation, where phosphorylated receptor-associated Smads associate with Smad4. SMIF (Smad4-interacting protein) and Smad4 form a complex with TGF-beta and BMP4, facilitating nuclear translocation. The SMIF gene is ubiquitously expressed and encodes a protein of approximately 70 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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