Thermo Fisher Scientific RICH2 Polyclonal Antibody
RICH2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응. Western blot 및 ELISA에 사용 가능하며, 고순도 Affinity Chromatography 정제. PBS/glycerol buffer에 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: []
ELISA
- Tested Dilution: 1 µg/mL
- Publications: []
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 666–772 of human ARHGAP44 (NP_055674.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.75 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914664 |
Product Specific Information
Positive test controls include:
- MCF7
- 293T
- Mouse brain, heart, lung
- Rat brain, heart
Target localization:
- Cell junction
- Cell projection
- Recycling endosome
- Dendritic spine
- Synapse
Immunogen sequence:
MADQSAGQPS PVSLSPTPPS TPSPYGLSYP QGYSLASGQL SPAAAPPLAS PSVFTSTLSK SRPTPKPRQR PTLPPPQPPT VNLSASSPQS TEAPMLDGMS PGESMST
Target Information
GTPase-activating protein (GAP) that stimulates GTPase activity of Rho-type GTPases, including CDC42 and RAC1.
In neurons, involved in dendritic spine formation and synaptic plasticity via RAC1-GAP activity.
Limits initiation of exploratory dendritic filopodia and recruits to actin patches that seed filopodia.
Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation.
Associates with SHANK3 to promote GRIA1 exocytosis and spine morphological changes linked to long-term potentiation.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-121092_RICH2_Q17R89-1_Rabbit.svg, PA5-121092_RICH2_Q17R89-1_Rabbit_PDP.jpeg)
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