Thermo Fisher Scientific hnRNP M3-M4 Monoclonal Antibody (2A6)
Thermo Fisher Scientific의 hnRNP M3-M4 단일클론 항체(2A6)는 Western blot, IHC, ICC, IP 등 다양한 응용에 적합합니다. Mouse IgG2b 형식으로 제작되었으며, rat 시료에서 검증되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:500 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:10–1:500 | - |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 | - |
| Immunoprecipitation (IP) | 1:10–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A6 |
| Immunogen | M19 fusion protein containing full-length human protein (hnRNP M3-M4, UniProt ID: P52272-1, antigen range: 1–730) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_1958837 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are proteins that directly bind to nascent RNA polymerase II transcripts and play an important role in transcript-specific packaging and alternative splicing of pre-mRNAs.
The M1–M4 proteins form a cluster of abundant hnRNPs that bind avidly to poly(G) and poly(U) RNA homopolymers in vitro.
These M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins, showing similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae.
They contain a unique hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif), similar to a repeat in the 64 kDa subunit of cleavage stimulation factor involved in pre-mRNA 3′-end maturation.
Proteins immunologically related to M exist in diverse eukaryotes ranging from human to yeast.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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