Thermo Fisher Scientific HIF-2 alpha Monoclonal Antibody (ep190b), DyLight 550

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:150-1:300

-

Immunocytochemistry (ICC/IF)

Assay-Dependent

-

Flow Cytometry (Flow)

1 µg

-

ELISA (ELISA)

Assay-Dependent

-

Product Specifications

Species Reactivity

Bovine, Hamster, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

ep190b

Immunogen

Human HIF-2 alpha amino acids 535-631. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HIF-2 alpha,uniProtId:Q99814-1,ncbiNodeId:9606,antigenRange:535-631,antigenLength:870,antigenImageFileName:MA5-16024_HIF-2_alpha_Q99814-1_House_mouse.svg,antigenImageFileNamePDP:MA5-16024_HIF-2_alpha_Q99814-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

DyLight™ 550 DyLight™ 550 DyLight™ 550

View additional formats

• Unconjugated
• Biotin
• DyLight 650
• HRP
• Request custom conjugation

Excitation/Emission Max

556/570 nm View spectra

Form

Liquid

Concentration

0.73 mg/mL

Purification

Protein G

Storage buffer

50mM sodium borate

Contains

0.05% sodium azide

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11156407

Target Information

HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.