Thermo Fisher Scientific CD98 Polyclonal Antibody
Western blot, IHC, IP 등 다양한 어플리케이션에 적합한 Rabbit Polyclonal CD98 항체. Human CD98 Heavy Chain(aa 580–630)을 면역원으로 제작. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도. 4°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | |
| Immunohistochemistry (IHC) | 1:500–1:2,000 | |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:2,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 580–630 of human CD98 Heavy Chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
CD98 (4F2) is a type II transmembrane glycoprotein that serves as the heavy chain of heterodimeric amino acid transporters (HATs).
It forms disulfide bonds with various light chains, enabling cell surface expression and basolateral localization in polarized epithelial cells.
CD98 also interacts with β1 integrins, enhancing their ligand affinity.
Beyond amino acid transport, CD98 is involved in cell fusion, activation, differentiation, growth, and apoptosis regulation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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