Thermo Fisher Scientific CD6 (Negative Marker of T-regulatory Cells) Monoclonal Antibody (SPV-L14)
CD6 단백질을 표적하는 SPV-L14 클론의 마우스 단클론 항체로, 인간 및 마우스 시료에 반응합니다. ICC/IF 및 유세포분석(Flow Cytometry)에 적합하며, 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능하며, T세포 활성화 및 면역 시냅스 연구에 유용합니다.
- 카탈로그번호
- 923-MSM3-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD6 (Negative Marker of T-regulatory Cells) Monoclonal Antibody (SPV-L14)
Thermo Fisher Scientific CD6 (Negative Marker of T-regulatory Cells) Monoclonal Antibody (SPV-L14)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPV-L14 |
| Immunogen | CD8+ cytotoxic T-cell clone |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL).
It interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and acts as a coreceptor for T cell activation and stabilizer of the immunological synapse.
CD6-ALCAM mediated cell adhesion plays an important role in T cell proliferation. CD6 may function through association with CD5, fine-tuning CD5 signaling.
Ligation of CD6 has an anti-apoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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