Thermo Fisher Scientific CD6 (Negative Marker of T-regulatory Cells) Monoclonal Antibody (SPM547)
인간 CD6 단백질을 인식하는 단클론 항체로, T-regulatory 세포의 음성 마커 분석에 적합합니다. IHC 및 ICC/IF 등 다양한 응용에 사용 가능하며, 고순도의 Protein A/G 정제 항체입니다. 연구용으로만 사용됩니다.
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- 923-MSM2X-P1ABX
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM547 |
| Immunogen | Human recombinant CD6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia (ALL) cells.
It interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and functions as a coreceptor for T cell activation and stabilizer of the immunological synapse.
CD6–ALCAM mediated adhesion contributes to T cell proliferation. CD6 may also modulate CD5 signaling and play an anti-apoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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