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Thermo Fisher Scientific PARN Polyclonal Antibody
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Thermo Fisher Scientific PARN Polyclonal Antibody

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Rabbit polyclonal antibody targeting human PARN protein for WB, IHC, and IP applications. High specificity to poly(A)-specific ribonuclease region (589–639). Supplied as unconjugated liquid at 1 mg/mL. Ideal for RNA metabolism and mRNA decay studies.

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pk
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Thermo Fisher Scientific A303562AM PARN Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
477,300원VAT 포함 525,030원
Thermo Fisher Scientific A303562AT PARN Polyclonal Antibody 10 ul pk판매 단위 pk ·
재고 확인 필요
194,600원VAT 포함 214,060원

Thermo Fisher Scientific · Thermo Fisher Scientific PARN Polyclonal Antibody

Thermo Fisher Scientific PARN Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution
Western Blot (WB) 1:2,000–1:10,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:500–1:2,000
Immunoprecipitation (IP) 2–10 µg/mg lysate

Product Specifications

Property Description
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Region between residue 589 and 639 of human Poly(A)-Specific Ribonuclease (Deadenylation Nuclease)
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Storage Conditions 4°C
Shipping Conditions Wet ice

Product Specific Information

  • Recommended shelf life: 1 year from date of receipt
  • For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Based on 100% sequence identity, this antibody is predicted to react with Orangutan

Target Information

The protein encoded by this gene is a 3′-exoribonuclease, similar to the RNase D family of 3′-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating eukaryotic mRNA decay. This protein is involved in silencing maternal mRNAs during oocyte maturation and early embryonic development, and participates in nonsense-mediated decay (NMD) of mRNAs with premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(해당 항원 구조 이미지: A303-562A-M_PARN_O95453-1_Rabbit.svg / A303-562A-M_PARN_O95453-1_Rabbit_PDP.jpeg)

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