Thermo Fisher Scientific PARN Polyclonal Antibody
PARN 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP에 적합하며 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제된 액상 형태로 4°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
- Note: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 589 and 639 of human Poly(A)-Specific Ribonuclease (Deadenylation Nuclease) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
The protein encoded by this gene is a 3'-exoribonuclease, similar to the RNase D family of 3'-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating mRNA decay. This protein also participates in silencing maternal mRNAs during oocyte maturation and early embryonic development, and in nonsense-mediated decay (NMD) of mRNAs with premature stop codons.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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