Thermo Fisher Scientific Phospho-BCL6 (Ser343) Polyclonal Antibody
인간 및 생쥐 시료에서 Ser343 위치의 인산화된 BCL6 단백질을 검출하는 폴리클로날 항체입니다. Western blot에 최적화되어 있으며, 고순도 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능하며 안정적인 PBS/glycerol 버퍼로 보관됩니다.
- 카탈로그번호
- PA5105969
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BCL6 (Accession P41182), corresponding to amino acid residues around phosphorylated Ser343 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817368 |
Product Specific Information
Antibody detects endogenous levels of Bcl6 only when phosphorylated at Ser343.
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and Bcl-6 rearrangements have been detected in 33%–45% of diffuse large B cell lymphomas.
Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and in nodular, lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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