Thermo Fisher Scientific Phospho-M1 Muscarinic Acetylcholine Receptor (Ser298) Polyclonal Antibody
인산화된 M1 무스카린 아세틸콜린 수용체(Ser298)를 인식하는 토끼 폴리클로날 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
- 카탈로그번호
- 7TM0013A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human M1 around the phosphorylation site of Ser298 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors.
The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation.
Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system.
The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract.
The gene encoding this receptor is localized to 11q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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