Thermo Fisher Scientific Phospho-PPAR gamma (Ser112) Polyclonal Antibody
PPAR gamma Ser112 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 응용 가능. Human, Mouse, Rat 반응성. 고순도 정제 및 PBS/glycerol 용액 형태로 제공. 연구용 전용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PPARG (Accession P37231), corresponding to amino acid residues around phosphorylated Ser112 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2816357 |
Product Specific Information
Antibody detects endogenous levels of PPAR gamma only when phosphorylated at Serine 112.
Target Information
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors.
PPARs form heterodimers with retinoid X receptors (RXRs), regulating transcription of various genes.
Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma.
The protein encoded by this gene, PPAR-gamma, regulates adipocyte differentiation and is implicated in diseases such as obesity, diabetes, atherosclerosis, and cancer.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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