Thermo Fisher Scientific TFF2 Polyclonal Antibody
TFF2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 등 연구용에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific TFF2 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000 dilution tested
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human TFF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719646 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds forming the trefoil motif (P-domain).
SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of gastric mucus, stabilizing glycoproteins through interactions with carbohydrate side chains.
Downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely involved in the early stages of gastric carcinogenesis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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