Thermo Fisher Scientific MCAF2 Polyclonal Antibody
Human MCAF2 단백질을 타깃으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용 전용 시약.
- 카탈로그번호
- PA559456
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MCAF2. Recombinant protein control fragment (Product #RP-98717). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643798 |
Product Specific Information
Immunogen sequence:
SVESPNLTTP ITSNPTDTRK ITSGNSSNSP NAEVMAVQKK LDSIIDLTKE GLSNCNTESP VSPLESHSKA ASNSKETTPL AQNAVQVPES FEHLPPLPEP PAPL
Highest antigen sequence identity to the following orthologs:
- Mouse: 58%
- Rat: 40%
Target Information
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 Lys-9 trimethylation (H3K9me3) activity (Probable). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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