Thermo Fisher Scientific Viperin Polyclonal Antibody
Thermo Fisher Scientific의 Viperin Polyclonal Antibody는 인간 Viperin 단백질을 인식하는 토끼 IgG 항체로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액 형태로 제공됩니다. 인터페론 유도 바이러스 단백질 연구에 활용됩니다.
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Viperin. Recombinant protein control fragment (Product #RP-98442) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649436 |
Product Specific Information
Immunogen sequence:
EAERFVIGDE EFERFLERHK EVSCLVPESN QKMKDSYLIL DEYMRFLNCR KGRKDPSKSI LDVGVEEAIK FSGFDEKMFL KRGGKYIWSK ADLKLDW
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 90%
Target Information
Viperin is a 43 kDa interferon-inducible viral protein. Its expression is elevated by LPS and poly I:C through TLR-dependent signaling pathways. Sendai virus-mediated viperin expression occurs independently of TLR signaling via RLRs (RIG-I and MAVs). Viperin plays an important role in interferon-mediated antiviral activity, notably in Hepatitis C virus models. It is induced in lymphoid and dendritic cells and highly expressed in neutrophils and macrophages during acute LCMV infection in mice.
Viperin functions as a mediator of viral resistance and a marker for interferon responsiveness, making its detection via specific antibody probes valuable for further studies.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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