Thermo Fisher Scientific MRPL3 Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 MRPL3 폴리클로날 항체. 사람 MRPL3 단백질에 특이적으로 반응하며, 고순도의 Affinity chromatography로 정제됨. 액상 형태로 안정적인 보관 가능하며 연구용으로 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MRPL3 (Accession P09001), corresponding to amino acid residues G43–G93. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854345 |
Product Specific Information
Antibody detects endogenous levels of total MRPL3.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are involved in mitochondrial protein synthesis. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes. Mammalian mitoribosomes lack a 5S rRNA, and their protein components vary significantly among species, making sequence homology recognition difficult. The MRPL3 gene encodes a 39S subunit protein from the L3P ribosomal protein family. A pseudogene corresponding to this gene is located on chromosome 13q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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