Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI1F8)

Applications

Flow Cytometry (Flow)

• Tested Dilution: 1:100–1:400

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

ICOS (CD278) encodes a protein belonging to the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and plays a crucial role in cell-cell signaling, immune responses, and regulation of cell proliferation.
Mutations or dysregulation of ICOS have been associated with disorders such as Common Variable Immunodeficiency (CVID).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.