Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI6F5)
Human ICOS 단백질을 인식하는 Mouse IgG1 단일클론 항체. Flow Cytometry에 최적화된 제품으로, 동결건조 형태로 제공되며 PBS와 8% 트레할로스 버퍼에 보관. 재구성 후 1 mg/mL 농도로 사용 가능.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:100–1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F5 |
| Immunogen | Full length human recombinant protein of human ICOS (NP_036224) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ICOS (CD278) encodes a member of the CD28 and CTLA-4 receptor family. It functions as a homodimer and plays a crucial role in cell-cell signaling, immune response regulation, and cell proliferation.
Mutations in ICOS are associated with Immunodeficiency, Common Variable, and related disorders.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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