Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI3H6), TrueMAB
인간 BFSP1 단백질을 표적으로 하는 단클론 항체로, Western Blot과 Immunohistochemistry에 적합. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능하며 안정적인 액상 형태로 공급.
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Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI3H6), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 405–665 of human BFSP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (phakinin) and filensin (product of BFSP1), are expressed only after fiber cell differentiation begins. Both proteins form the beaded filament (BF), a unique cytoskeletal element.
Mutations in BFSP1 cause autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been identified.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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