Thermo Fisher Scientific STRN3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human STRN3. Recombinant protein control fragment (Product #RP-89110).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648044

Product Specific Information

Immunogen sequence: LGLSNSEPNG SVETKNLEQI LNGGESPKQK GQEIKRSSGD VLETFNFLEN ADDSDEDEEN DMIEGIPEGK DKHRMNKHKI GNEGLAADLT DDPDTEEALK EFDFLVTAED GEGAGEARSS GDGTEWAEPI TFPSGGGKS

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

Target Information

SG2NA was identified as a human cancer autoantigen and has now been implicated in vesicular trafficking and signal transduction. It is highly related to striatin and zinedin. It is a scaffolding protein that binds PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which has been implicated in control of mitotic progression in yeast. It also binds calmodulin and appears to modulate PP2A activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.