Thermo Fisher Scientific Galactosidase alpha Polyclonal Antibody
Galactosidase alpha 단백질 검출용 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 응용 분야(WB, IHC, ICC, Flow, ELISA)에 사용 가능하며, 고순도 Protein A 정제. 인간, 생쥐, 랫트 반응성. 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Galactosidase alpha, amino acids 101–200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyzes the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. The enzyme predominantly hydrolyzes ceramide trihexoside and can catalyze the hydrolysis of melibiose into galactose and glucose. Mutations in this gene affect enzyme synthesis, processing, and stability, leading to Fabry disease — a rare lysosomal storage disorder resulting from failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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