Thermo Fisher Scientific NR4A3 Monoclonal Antibody (OTI2A6), TrueMAB
Human NR4A3 단백질(aa 332-626)에 특이적인 Mouse monoclonal antibody로 Western blot 및 IHC(P) 적용 가능. Lyophilized 형태로 제공되며, PBS buffer(8% trehalose) 내 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 332–626 of human NR4A3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NOR-1 (NR4A3) is a NR4 nerve growth factor-like receptor involved in neuronal development, T-cell apoptosis, and cancer progression.
It binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene.
NOR-1 expression is rapidly and transiently induced by various stimuli.
Downregulation of NOR-1 and related NGFI-B family members correlates with drug addiction-prone behavior in Lewis rats.
Three human isoforms have been documented: NOR-1, NOR-1β, and NOR-1 3′ variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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