Thermo Fisher Scientific GABRA1 Polyclonal Antibody
Zebrafish Gabra1을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS와 20% glycerol에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | The immunogen used to generate this antibody corresponds to zebrafish Gabra1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090433 |
Target Information
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing hyperpolarization of the membrane through the opening of a Cl⁻ channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for sedative, anxiolytic, and hypnotic agents and are implicated in diseases such as epilepsy, anxiety, depression, and substance abuse.
The GABAA-R is a multimeric subunit complex with multiple alpha, beta, and gamma subunits, including splice variants. Expression of alpha and beta subunits alone produces GABA-sensitive receptors, but coexpression with a gamma subunit is required for benzodiazepine modulation. Phosphorylation of beta subunits can modulate receptor function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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