Thermo Fisher Scientific PADI4 Polyclonal Antibody
Human PADI4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications
- Western Blot (WB): 1:500–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–44 of PAD4 (Uniprot ID: Q9UM07) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2552054 |
Product Specific Information
- Recommended positive controls: PAD4-transfected 293T
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Catalyzes the citrullination/deimination of arginine residues of proteins.
Citrullinates histone H3 at Arg-8 and/or Arg-17 and histone H4 at Arg-3, which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription.
Citrullinates EP300/P300 at Arg-2142, which favors its interaction with NCOA2/GRIP1.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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