Thermo Fisher Scientific CBX6 Polyclonal Antibody
CBX6 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. ICC/IF 실험에 적합하며, 고순도 Affinity chromatography로 정제되었습니다. PBS 기반의 안정적 보관용액 포함, 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 271–337. Recombinant protein control fragment (Product #RP-109962). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091877 |
Product Specific Information
- Immunogen sequence: RSSGSSGCPS PTPQSSDPDD TPPKLLPETV SPSAPSWREP EVLDLSLPPE SAATSKRAPP EVTAAAG
- Antigen sequence identity: Mouse 75%; Rat 78%
Target Information
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes.
CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex.
Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes.
Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (Chromatin Organization Modifier) domain, which plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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