Thermo Fisher Scientific CLC-K Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:200

Product Specifications

Product Specific Information

Reconstitution: Add 50 µL or 0.2 mL of double distilled water (DDW), depending on sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C. The reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, prepare small aliquots and keep at -20°C. Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which includes at least nine mammalian chloride channels. Each channel is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB cause autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence), and both expressed in the mammalian kidney.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.