Thermo Fisher Scientific ACAT2 Monoclonal Antibody (OTI5F7), TrueMAB
ACAT2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC/IF, Flow cytometry에 적합합니다. Human, Dog, Rat 시료에 반응하며, 고순도의 Affinity chromatography 정제 항체입니다. 연구용으로 안정적인 -20°C 보관이 가능합니다.
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Applications 및 희석 배율
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F7 |
| Immunogen | Full length human recombinant protein of human ACAT2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The encoded protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains. Unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. It functions as a negative regulator of the canonical Wnt/β-catenin signaling cascade, inhibiting oncogenic transformation, cell proliferation, and suppression of apoptosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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