Thermo Fisher Scientific ACAT2 Monoclonal Antibody (OTI7B1), TrueMAB
ACAT2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry 등에 사용 가능. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용.
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Applications 및 권장 희석 배율
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B1 |
| Immunogen | Full length human recombinant protein of human ACAT2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins that act as receptors for Wnt signaling proteins.
The protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains.
Unlike other family members, this protein lacks a C-terminal PDZ domain-binding motif.
It functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, inhibiting oncogenic transformation, cell proliferation, and apoptosis inhibition.
Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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배송/결제/교환/반품 안내
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