Thermo Fisher Scientific ACAT2 Monoclonal Antibody (OTI3C9), TrueMAB
ACAT2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC/IF, Flow cytometry에 적합. Human, Dog, Rat 반응성. 고순도 Affinity chromatography 정제, 안정적 PBS/BSA/glycerol buffer 구성. 연구용 전용 시약.
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Applications 및 Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C9 |
| Immunogen | Full length human recombinant ACAT2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins acting as receptors for Wnt signaling proteins.
The encoded protein contains a signal peptide, a cysteine-rich extracellular domain, and seven transmembrane domains but lacks a C-terminal PDZ-binding motif.
It functions as a negative regulator of the canonical Wnt/beta-catenin signaling pathway, inhibiting oncogenic transformation, cell proliferation, and apoptosis suppression.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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