Thermo Fisher Scientific IKK alpha Polyclonal Antibody
IKK alpha 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성. IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적인 액상 형태, -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human IKK alpha, amino acids 551–650 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine-activated protein complex that inhibits the NF-kappa B complex. IKK alpha, together with IKK beta and the regulatory protein NEMO (IKK gamma), phosphorylates IkB proteins, targeting them for ubiquitin-mediated degradation. This kinase plays a crucial role in inflammation and cell survival processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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