Thermo Fisher Scientific rRNA Monoclonal Antibody (Y10b)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

-

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Immunohistochemistry (PFA fixed) (IHC (PFA))

-

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Immunocytochemistry (ICC/IF)

2 µg/mL

-

Immunoprecipitation (IP)

Assay-dependent

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Many

Published species

Fruit fly, Mouse, Zebrafish

Host/Isotype

Mouse / IgG3, kappa

Class

Monoclonal

Type

Antibody

Clone

Y10b

Immunogen

Whole ribosomal rRNA 5.8S

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10979967

Product Specific Information

This clone recognizes both the large and the small subunit of rRNA from all eukaryotic cells.

MA1-13017 has been successfully used in Immunocytochemistry, immunoprecipitation, immunofluorescence applications.

The MA1-13017 immunogen is from whole ribosomal rRNA 52.8S

Target Information

rRNA (ribosomal RNA) forms a major structural component of ribosomes which provides a mechanism for decoding mRNA information into amino acids/proteins through the process of translation. rRNA plays a key role in accurate positioning of mRNA as well as peptidyl tRNA, and also plays a structural role in peptidyl transferase activity by generating scaffolds where ribosomal proteins are assembled. rRNA is generated inside nucleolus, which is localized in nucleus of the cells and contains genes essential for encoding rRNA. Defective rRNA may implicate in certain pathologies, for example: decreased rRNA expression has been observed in subjects with myelodysplastic syndromes, and abnormal rRNA expression has also been linked to Alzheimer`s disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.