Thermo Fisher Scientific ESRRA Monoclonal Antibody (1A6E11)
Human ESRRA 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, Flow cytometry, ELISA에 사용 가능. 단백질 G 정제, 1 mg/mL 농도, PBS buffer에 sodium azide 포함. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A6E11 |
| Immunogen | Purified recombinant fragment of human ESRRA (aa: 198–376) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898430 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan nuclear hormone receptor. Members of the ERR family share a highly conserved DNA-binding domain with 68% amino acid identity to the estrogen receptor. ERRα binds to an ERRα response element (ERRE) containing a single consensus half-site (5'-tnaaggtca-3') and can interact with the medium-chain acyl-CoA dehydrogenase (MCAD) response element NRRE-1. It acts as a metabolic regulator, predominantly expressed in tissues metabolizing fatty acids. The corresponding gene is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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