Thermo Fisher Scientific Chemerin Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Chemerin 폴리클로날 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 고순도(>95%) 항체로 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA575669
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- pk
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human Chemerin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719397 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also known as retinoic acid receptor responder proteins, can be membrane-bound or secreted. TIGs function as tumor suppressor genes and are highly expressed in skin, hair follicles, endothelial cells, pancreas, spleen, and intestine. TIG2, a secreted protein, is mainly expressed in epidermis, hair follicles, and endothelial cells, and is inhibited in psoriatic lesions but activated by tazarotene. TIG2 mediates the growth suppressive effects of retinoids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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