Thermo Fisher Scientific TFF2 Polyclonal Antibody
TFF2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 점막 보호 및 위장관 연구용으로 적합합니다.
- 카탈로그번호
- PA575670
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:1,000
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human TFF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719398 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds forming the trefoil motif (P-domain).
Trefoil factor 2 (TFF2), also known as spasmolytic polypeptide (SP), functions to inhibit gastrointestinal motility and gastric acid secretion. It may act as a structural component of gastric mucus by stabilizing glycoproteins through interactions with carbohydrate side chains.
Downregulation of SP expression is associated with primary gastric cancer, and progressive loss of this protein may be involved in early stages of gastric carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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