Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI1E6), TrueMAB
Human ESRRA 단백질(aa 1-205)을 면역원으로 한 Mouse monoclonal antibody. Western blot에 1:500 희석 사용 권장. Affinity chromatography로 정제된 1 mg/mL 액상 제품. -20°C 보관, 동결/해동 반복 피해야 함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–205 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily. ERR family members share an almost identical DNA-binding domain, showing 68% amino acid identity with that of the estrogen receptor. ERRα binds to an ERR-alpha response element (ERRE) containing a single consensus half-site (5'-tnaaggtca-3') and can interact with the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element (NRRE-1). It may act as an important regulator of the MCAD promoter and functions as a metabolic regulator, often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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