Thermo Fisher Scientific GluR3 Monoclonal Antibody (1D2)

Applications and Tested Dilution

Product Specifications

Product Specific Information

MA5-15869 targets GRIA3 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human GRIA3 expressed in E. coli.
MA5-15869 detects GRIA3, which has a predicted molecular weight of approximately 101 kDa.

Target Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits forming ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors and is subject to RNA editing (AGA→GGA; R→G). Alternative splicing at this locus results in different isoforms, which may vary in signal transduction properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.