Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI20G10), TrueMAB
인간 PD-L1(CD274)에 특이적인 마우스 단클론 항체로, Western blot 및 유세포분석에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 저장 버퍼 사용. 암 면역 회피 연구에 활용 가능.
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Applications
- Western Blot (WB): Assay-dependent
- Flow Cytometry (Flow): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI20G10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–290 of human CD274 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. This interaction decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be up-regulated by IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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