Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI9E10), TrueMAB
인간 PD-L1(CD274)을 표적으로 하는 Mouse IgG1 단클론 항체로 Western blot 및 유세포 분석에 적합함. 비결합형 액상 형태로 1 mg/mL 농도이며, PBS/BSA/glycerol 용액에 보관. 종양 면역 회피 연구용으로 사용.
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–290 of human CD274 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor, PD-1, which negatively regulates T-cell receptor (TCR) signaling. Ligating PD-1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant on many murine and human cancers and can be upregulated upon IFN-gamma stimulation, suggesting a role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명 예시: TA810744_PD-L1_CD274_Q9NZQ7-1_House_mouse.svg, TA810744_PD-L1_CD274_Q9NZQ7-1_House_mouse_PDP.jpeg)
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