Thermo Fisher Scientific ZHX2 Monoclonal Antibody (OTI2E2), TrueMAB
ZHX2 단백질을 특이적으로 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 고순도의 Affinity chromatography 정제 및 안정한 PBS/BSA/glycerol 버퍼로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 595–837 of human ZHX2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1–3 are ubiquitously expressed in various tissues and act as transcriptional repressors localized in the nucleus.
These proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs), allowing them to form homo- and heterodimers. Dimerization is not essential for repressor activity.
Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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