Thermo Fisher Scientific PEPT1 Polyclonal Antibody
Western blot, IHC, Flow cytometry, ELISA 등 다양한 응용에 적합한 PEPT1 폴리클로날 항체. Rabbit IgG 기반으로 높은 특이성과 재현성을 제공. Bovine, Chicken, Human, Mouse, Rat 반응성. 단백질 흡수 연구 및 영양·약리학 연구용.
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- BS-0689R
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Flow Cytometry (Flow) | 1:50 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Chicken, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from chicken PEPT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In mammalian small intestine, the proton-coupled peptide transporter (PEPT) is responsible for the absorption of small peptides arising from digestion of dietary proteins.
PEPT1, a hydrogen ion/peptide cotransporter, transports dipeptides and tripeptides, but not free amino acids or peptides with more than three amino acid residues.
Its driving force for uphill transport requires proton binding and the presence of an inside-negative membrane potential.
PEPT1 is a 708 amino acid protein containing 12 putative membrane-spanning domains and is expressed in Caco-2 cells.
PEPT1 plays important roles in nutritional and pharmacological therapies.
The mammalian kidney expresses a proton-coupled peptide transporter, PEPT2, responsible for the absorption of small peptides and peptide-like drugs such as beta-lactam antibiotics from the tubular filtrate.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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