Thermo Fisher Scientific PLAGL1 Polyclonal Antibody
인간 PLAGL1 단백질을 인식하는 Rabbit Polyclonal 항체. ICC/IF에 사용 가능하며 0.25–2 µg/mL 농도로 최적화됨. 항원 친화 크로마토그래피로 정제되었으며 PBS(40% 글리세롤) 완충액에 보관. 종양 억제 유전자 연구 및 TNDM 관련 연구에 적합.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PLAGL1. Recombinant protein control fragment (Product #RP-105023) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2665151 |
Product Specific Information
Immunogen sequence:
QELMKESLQTG DLLSTFHTIS PSFQLKAAAL PPFPLGASAQ NGLASSLPAE VHSLTLSPPE QAAQPMQPLP ESLASLHPSV SPGSP- Highest antigen sequence identity to orthologs: mouse 50%, rat 47%
Target Information
This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has anti-proliferative properties and is thought to function as a tumor suppressor. Overexpression during fetal development is associated with transient neonatal diabetes mellitus (TNDM). The gene is imprinted with preferential paternal expression, though biallelic expression occurs in peripheral blood leukocytes. Tissue-specific imprinting results from variable promoter utilization. Multiple transcript variants exist, differing in the 5′ UTR and encoding two isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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