Thermo Fisher Scientific CAND1 Polyclonal Antibody
Thermo Fisher Scientific의 CAND1 Polyclonal Antibody는 인간 CAND1 단백질을 인식하는 토끼 다클론 항체입니다. Western blot과 면역세포화학(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CAND1. Recombinant protein control fragment (Product #RP-105025) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663902 |
Product Specific Information
Immunogen sequence:
DALSCLYVILC NHSPQVFHPH VQALVPPVVA CVGDPFYKIT SEALLVTQQL VKVIRPLDQP SSFDATPYIK DLFTCT
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins.
CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. It disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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