Thermo Fisher Scientific Human CCP110 Synthetic Peptide
Human CCP110 단백질의 17 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 차단용으로 사용 가능하며, 세포 중심체 복제 및 섬모 형성 조절 연구에 적합. 액상 형태로 제공되며 PBS 버퍼에 0.1% BSA 포함. 연구용 전용 제품.
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Thermo Fisher Scientific Human CCP110 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 17 amino acid sequence near the carboxy terminus of human CCP110.
PEP-1423 can be used as a blocking peptide with polyclonal antibody PA5-34380.
Target Information
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole, thereby preventing cilia formation (PubMed:17719545, PubMed:17681131, PubMed:23486064).
Also involved in promoting ciliogenesis and may play a role in the assembly of the mother centriole subdistal appendages (SDA), affecting the fusion of recycling endosomes to basal bodies during cilia formation.
Required for correct spindle formation and plays a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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