Thermo Fisher Scientific TNFAIP8 Polyclonal Antibody
TNFAIP8 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며, 인간에 반응하고 마우스·랫 등 다양한 종에 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C 단기 보관 및 -20°C 장기 보관 권장.
- 카탈로그번호
- PA529401
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length human TNFAIP8 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546877 |
Product Specific Information
- Recommended positive controls: A431, HeLa
- Predicted reactivity: Mouse (94%), Rat (93%), Xenopus laevis (84%), Pig (95%), Chicken (89%), Rhesus Monkey (98%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TNFalpha-IP 8 (tumor necrosis factor, alpha-induced protein 8), also known as NFkappa B-inducible DED-containing protein (NDED), SCC-S2, or TNF-induced protein GG2-1, is a 198 amino acid cytoplasmic protein induced by NFkappa B and TNF.
The induction of TNFalpha-IP 8 by TNF is dependent on NFkappa B activation.
It negatively mediates apoptosis and may play a role in tumor progression. TNFalpha-IP 8 inhibits caspase-8 activity, preventing BID cleavage and caspase-3 activation during TNF-mediated apoptosis.
It is expressed at high levels in thymus, bone marrow, lymph node, spleen, thyroid, placenta, and various tumor tissues, as well as fetal lung, liver, and kidney.
TNFalpha-IP 8 exists as three isoforms produced by alternative splicing.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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