Thermo Fisher Scientific STUB1 Monoclonal Antibody (02)
Human STUB1 단백질에 특이적인 마우스 모노클로날 항체. ELISA에 최적화된 고순도 Protein A 정제 항체. 방부제 무첨가로 장기 보관 시 sodium azide 추가 권장. 연구용으로만 사용 가능.
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Applications
ELISA
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 02 |
| Immunogen | Recombinant Human STUB1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786585 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human STUB1.
Target Information
A recently identified protein, termed carboxyl terminus of hsc70-interacting protein (CHIP), interacts with both the constitutive form of hsc70 and the stress-inducible form hsp70. This 35 kDa cytoplasmic protein is highly expressed in striated muscle and across a wide range of cultured tissues.
Through immunoprecipitation experiments, CHIP has been shown to directly bind to the carboxyl terminus of hsc70 and hsp70, decreasing ATPase activity and reducing chaperone efficiency.
CHIP also functions in the ubiquitin-proteasome system as an E3 ubiquitin-ligase via its U-box domain, in conjunction with hsc70 and hsp90.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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