Thermo Fisher Scientific ANP32C Polyclonal Antibody
Human ANP32C 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 Immunocytochemistry에 사용 가능. Affinity chromatography로 정제된 액상 시약이며, PBS/glycerol buffer에 보관. 종양 관련 ANP32C 연구에 적합.
- 카탈로그번호
- PA5101062
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ANP32C (Accession O43423), corresponding to amino acid residues N125–Y175 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850506 |
Product Specific Information
Antibody detects endogenous levels of total ANP32C.
Target Information
ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 or tumorigenic protein pp32r1, is a 234 amino acid protein containing 4 leucine-rich repeats and belongs to the ANP32 family.
ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits prostate and breast cancers.
Although similar to ANP32A, ANP32C is tumorigenic and expressed in activated stem cells (mobilized CD34+ and cord blood CD34+ cells), but not in resting bone marrow CD34+ cells.
It is also found in various neoplastic cell lines, mainly prostatic adenocarcinoma, and may modulate the oncogenic potential of human prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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