Thermo Fisher Scientific Phospho-SMC1 (Ser966) Polyclonal Antibody
SMC1 단백질의 Ser966 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. WB, IHC, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-SMC1 (Ser966) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human SMC1 around the phosphorylation site of S966 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607834 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins are essential for nuclear processes that involve chromosome structural changes, including mitotic chromosome organization, DNA recombination and repair, and transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion during mitosis.
Mutations in the SMC1 gene can lead to Cornelia de Lange syndrome 2.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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